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Silencing of genes by promoter hypermethylation shapes tumor microenvironment and resistance to immunotherapy in clear-cell renal cell carcinomas.
Lu, Xiaofan; Vano, Yann-Alexandre; Su, Xiaoping; Helleux, Alexandra; Lindner, Véronique; Mouawad, Roger; Spano, Jean-Philippe; Rouprêt, Morgan; Compérat, Eva; Verkarre, Virginie; Sun, Cheng-Ming; Bennamoun, Mostefa; Lang, Hervé; Barthelemy, Philippe; Cheng, Wenxuan; Xu, Li; Davidson, Irwin; Yan, Fangrong; Fridman, Wolf Hervé; Sautes-Fridman, Catherine; Oudard, Stéphane; Malouf, Gabriel G.
Afiliação
  • Lu X; Department of Cancer and Functional Genomics, Institute of Genetics and Molecular and Cellular Biology, CNRS/INSERM/UNISTRA, 67400 Illkirch, France.
  • Vano YA; Department of Medical Oncology, Hôpital Européen Georges Pompidou, Institut du Cancer Paris CARPEM, AP-HP, Université Paris Cité, Paris, France; Centre de Recherche Cordeliers, INSERM 1138, Université de Paris Cité, Sorbonne Université, Equipe labellisée Ligue contre le Cancer, 75006 Paris, France.
  • Su X; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Helleux A; Department of Cancer and Functional Genomics, Institute of Genetics and Molecular and Cellular Biology, CNRS/INSERM/UNISTRA, 67400 Illkirch, France.
  • Lindner V; Department of Pathology, Strasbourg University Hospital, Strasbourg, France.
  • Mouawad R; Department of Medical Oncology, Sorbonne University, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.
  • Spano JP; Department of Medical Oncology, Sorbonne University, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.
  • Rouprêt M; Sorbonne University, GRC 5 P, UKredictive Onco-Uro, AP-HP, Urology, Pitié-Salpêtrière Hospital, 75013 Paris, France.
  • Compérat E; Department of Pathology, Sorbonne University, AP-HP, Hôpital Tenon, Paris, France.
  • Verkarre V; Department of Pathology, Hôpital Européen Georges Pompidou, Institut du Cancer Paris CARPEM, AP-HP, Université Paris Cité, Paris, France.
  • Sun CM; Centre de Recherche Cordeliers, INSERM 1138, Université de Paris Cité, Sorbonne Université, Equipe labellisée Ligue contre le Cancer, 75006 Paris, France.
  • Bennamoun M; Department of Medical Oncology, Institut Mutualiste Montsouris, Paris, France.
  • Lang H; Department of Urology, Strasbourg University Hospital, Strasbourg, France.
  • Barthelemy P; Department of Medical Oncology, Strasbourg University, Institut de Cancérologie de Strasbourg, Strasbourg, France.
  • Cheng W; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P.R. China.
  • Xu L; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P.R. China.
  • Davidson I; Department of Cancer and Functional Genomics, Institute of Genetics and Molecular and Cellular Biology, CNRS/INSERM/UNISTRA, 67400 Illkirch, France.
  • Yan F; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P.R. China.
  • Fridman WH; Centre de Recherche Cordeliers, INSERM 1138, Université de Paris Cité, Sorbonne Université, Equipe labellisée Ligue contre le Cancer, 75006 Paris, France.
  • Sautes-Fridman C; Centre de Recherche Cordeliers, INSERM 1138, Université de Paris Cité, Sorbonne Université, Equipe labellisée Ligue contre le Cancer, 75006 Paris, France.
  • Oudard S; Centre de Recherche Cordeliers, INSERM 1138, Université de Paris Cité, Sorbonne Université, Equipe labellisée Ligue contre le Cancer, 75006 Paris, France.
  • Malouf GG; Department of Cancer and Functional Genomics, Institute of Genetics and Molecular and Cellular Biology, CNRS/INSERM/UNISTRA, 67400 Illkirch, France; Department of Medical Oncology, Strasbourg University, Institut de Cancérologie de Strasbourg, Strasbourg, France. Electronic address: maloufg@igbmc.fr
Cell Rep Med ; 4(11): 101287, 2023 11 21.
Article em En | MEDLINE | ID: mdl-37967556
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Neoplasias Renais Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Neoplasias Renais Idioma: En Ano de publicação: 2023 Tipo de documento: Article