Echinococcus granulosus cyst fluid inhibits KDM6B-mediated demethylation of trimethylated histone H3 lysine 27 and interleukin-1ß production in macrophages.

Lin, Ruolin; Wang, Xiaopeng; Ni, Caiya; Fu, Chunxue; Yang, Chun; Dong, Dan; Wu, Xiangwei; Chen, Xueling; Wang, Lianghai; Hou, Jun

Lin, Ruolin; Wang, Xiaopeng; Ni, Caiya; Fu, Chunxue; Yang, Chun; Dong, Dan; Wu, Xiangwei; Chen, Xueling; Wang, Lianghai; Hou, Jun.

Afiliação

Lin R; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi University School of Medicine, Shihezi, Xinjiang, China.
Wang X; Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Shihezi University School of Medicine, Shihezi, Xinjiang, China.
Ni C; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi University School of Medicine, Shihezi, Xinjiang, China.
Fu C; Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Shihezi University School of Medicine, Shihezi, Xinjiang, China.
Yang C; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi University School of Medicine, Shihezi, Xinjiang, China.
Dong D; Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Shihezi University School of Medicine, Shihezi, Xinjiang, China.
Wu X; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi University School of Medicine, Shihezi, Xinjiang, China.
Chen X; Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Shihezi University School of Medicine, Shihezi, Xinjiang, China.
Wang L; NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, Shihezi University School of Medicine, Shihezi, Xinjiang, China.
Hou J; Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Shihezi University School of Medicine, Shihezi, Xinjiang, China.

Parasit Vectors ; 16(1): 422, 2023 Nov 16.

Article em En | MEDLINE | ID: mdl-37974225

Assuntos

Echinococcus granulosus; Histonas; Animais; Criança; Humanos; Camundongos; Líquido Cístico/metabolismo; Desmetilação; Echinococcus granulosus/metabolismo; Histonas/metabolismo; Interleucina-1beta/genética; Interleucina-1beta/metabolismo; Histona Desmetilases com o Domínio Jumonji/genética; Lisina/metabolismo; Lisina/farmacologia; Macrófagos; Proteína 3 que Contém Domínio de Pirina da Família NLR/genética; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

Cystic echinococcosis; KDM6B; NLRP3 inflammasome; Trimethylated histone H3 lysine 27

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Echinococcus granulosus Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Echinococcus granulosus Idioma: En Ano de publicação: 2023 Tipo de documento: Article