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Direct inhibition of dioxygenases TET1 by the rheumatoid arthritis drug auranofin selectively induces cancer cell death in T-ALL.
Chen, Long; Ren, Anqi; Zhao, Yuan; Chen, Hangyu; Wu, Qifang; Zheng, Mengzhu; Zhang, Zijian; Zhang, Tongcun; Zhong, Wu; Lin, Jian; Zhu, Haichuan.
Afiliação
  • Chen L; Department of Pharmacy, Peking University Third Hospital Cancer Center, Peking University Third Hospital, Peking University, Beijing, 100191, China.
  • Ren A; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Wuhan, 430081, China.
  • Zhao Y; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Wuhan, 430081, China.
  • Chen H; Department of Pharmacy, Peking University Third Hospital Cancer Center, Peking University Third Hospital, Peking University, Beijing, 100191, China.
  • Wu Q; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Wuhan, 430081, China.
  • Zheng M; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Wuhan, 430081, China.
  • Zhang Z; Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Song Li's Academician Workstation of Hainan University, Hainan University, Sanya, 572000, China.
  • Zhang T; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Wuhan, 430081, China.
  • Zhong W; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Wuhan, 430081, China.
  • Lin J; National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China. zhongwu@bmi.ac.cn.
  • Zhu H; Department of Pharmacy, Peking University Third Hospital Cancer Center, Peking University Third Hospital, Peking University, Beijing, 100191, China. linjian@pku.edu.cn.
J Hematol Oncol ; 16(1): 113, 2023 11 22.
Article em En | MEDLINE | ID: mdl-37993905
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Dioxigenases / Leucemia-Linfoma Linfoblástico de Células T Precursoras Idioma: En Ano de publicação: 2023 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Dioxigenases / Leucemia-Linfoma Linfoblástico de Células T Precursoras Idioma: En Ano de publicação: 2023 Tipo de documento: Article