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DGKα/ζ inhibition lowers the TCR affinity threshold and potentiates antitumor immunity.
Kureshi, Rakeeb; Bello, Elisa; Kureshi, Courtney T S; Walsh, Michael J; Lippert, Victoria; Hoffman, Megan T; Dougan, Michael; Longmire, Tyler; Wichroski, Michael; Dougan, Stephanie K.
Afiliação
  • Kureshi R; Department of Immunology, Harvard Medical School, Boston, MA, USA.
  • Bello E; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Kureshi CTS; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Walsh MJ; Department of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA.
  • Lippert V; Department of Immunology, Harvard Medical School, Boston, MA, USA.
  • Hoffman MT; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Dougan M; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Longmire T; Department of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA.
  • Wichroski M; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Dougan SK; Department of Immunology, Harvard Medical School, Boston, MA, USA.
Sci Adv ; 9(47): eadk1853, 2023 11 24.
Article em En | MEDLINE | ID: mdl-38000024

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diglicerídeos / Neoplasias Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diglicerídeos / Neoplasias Idioma: En Ano de publicação: 2023 Tipo de documento: Article