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WarpDrive: Improving spatial normalization using manual refinements.
Oxenford, Simón; Ríos, Ana Sofía; Hollunder, Barbara; Neudorfer, Clemens; Boutet, Alexandre; Elias, Gavin J B; Germann, Jurgen; Loh, Aaron; Deeb, Wissam; Salvato, Bryan; Almeida, Leonardo; Foote, Kelly D; Amaral, Robert; Rosenberg, Paul B; Tang-Wai, David F; Wolk, David A; Burke, Anna D; Sabbagh, Marwan N; Salloway, Stephen; Chakravarty, M Mallar; Smith, Gwenn S; Lyketsos, Constantine G; Okun, Michael S; Anderson, William S; Mari, Zoltan; Ponce, Francisco A; Lozano, Andres; Neumann, Wolf-Julian; Al-Fatly, Bassam; Horn, Andreas.
Afiliação
  • Oxenford S; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. Electronic address: simon.oxenford@charite.de.
  • Ríos AS; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Hollunder B; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Einstein Center for Neurosciences Berlin, Charité - Universitätsmedizin Berlin, Berlin, Germany
  • Neudorfer C; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Brain Modulation Lab, Department of Neurosurgery, Massachusetts General Hospital, Boston, MA 02
  • Boutet A; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON M5T2S8, Canada; Krembil Research Institute, University of Toronto, Toronto, ON M5T2S8, Canada; Joint Department of Medical Imaging, University of Toronto, Toronto, ON M5T1W7, Canada.
  • Elias GJB; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON M5T2S8, Canada; Krembil Research Institute, University of Toronto, Toronto, ON M5T2S8, Canada.
  • Germann J; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON M5T2S8, Canada; Krembil Research Institute, University of Toronto, Toronto, ON M5T2S8, Canada.
  • Loh A; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON M5T2S8, Canada; Krembil Research Institute, University of Toronto, Toronto, ON M5T2S8, Canada.
  • Deeb W; UMass Chan Medical School, Department of Neurology, Worcester, MA 01655, United States; UMass Memorial Health, Department of Neurology, Worcester, MA 01655, United States.
  • Salvato B; University of Florida Health Jacksonville, Jacksonville, FL, United States.
  • Almeida L; Department of Neurology, University of Minnesota, Twin Cities Campus, Minneapolis, MN, United States.
  • Foote KD; Norman Fixel Institute for Neurological Diseases, Departments of Neurology and Neurosurgery, University of Florida, Gainesville, FL, United States.
  • Amaral R; Cerebral Imaging Centre, Douglas Research Centre, Montreal, QC, Canada.
  • Rosenberg PB; Department of Psychiatry and Behavioral Sciences and Richman Family Precision Medicine Center of Excellence, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.
  • Tang-Wai DF; Krembil Research Institute, University of Toronto, Toronto, ON M5T2S8, Canada; Department of Medicine, Division of Neurology, University Health Network and University of Toronto, Toronto, ON M5T2S8, Canada.
  • Wolk DA; Department of Neurology, University of Pennsylvania, Philadelphia, PA, United States.
  • Burke AD; Barrow Neurological Institute, Phoenix, AZ, United States.
  • Sabbagh MN; Barrow Neurological Institute, Phoenix, AZ, United States.
  • Salloway S; Department of Psychiatry and Human Behavior and Neurology, Alpert Medical School of Brown University, Providence, RI, United States; Memory & Aging Program, Butler Hospital, Providence, United States.
  • Chakravarty MM; Cerebral Imaging Centre, Douglas Research Centre, Montreal, QC, Canada; Department of Psychiatry, McGill University, Montreal, QC, Canada; Biological and Biomedical Engineering, McGill University, Montreal, QC, Canada.
  • Smith GS; Cerebral Imaging Centre, Douglas Research Centre, Montreal, QC, Canada.
  • Lyketsos CG; Cerebral Imaging Centre, Douglas Research Centre, Montreal, QC, Canada.
  • Okun MS; Norman Fixel Institute for Neurological Diseases, Departments of Neurology and Neurosurgery, University of Florida, Gainesville, FL, United States.
  • Anderson WS; Johns Hopkins School of Medicine, Baltimore, MD, United States.
  • Mari Z; Johns Hopkins School of Medicine, Baltimore, MD, United States; Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, United States.
  • Ponce FA; Barrow Neurological Institute, Phoenix, AZ, United States.
  • Lozano A; Division of Neurosurgery, Department of Surgery, University Health Network and University of Toronto, Toronto, ON M5T2S8, Canada; Krembil Research Institute, University of Toronto, Toronto, ON M5T2S8, Canada.
  • Neumann WJ; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Al-Fatly B; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Horn A; Movement Disorders and Neuromodulation Unit, Department of Neurology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Brain Modulation Lab, Department of Neurosurgery, Massachusetts General Hospital, Boston, MA 02
Med Image Anal ; 91: 103041, 2024 Jan.
Article em En | MEDLINE | ID: mdl-38007978
ABSTRACT
Spatial normalization-the process of mapping subject brain images to an average template brain-has evolved over the last 20+ years into a reliable method that facilitates the comparison of brain imaging results across patients, centers & modalities. While overall successful, sometimes, this automatic process yields suboptimal results, especially when dealing with brains with extensive neurodegeneration and atrophy patterns, or when high accuracy in specific regions is needed. Here we introduce WarpDrive, a novel tool for manual refinements of image alignment after automated registration. We show that the tool applied in a cohort of patients with Alzheimer's disease who underwent deep brain stimulation surgery helps create more accurate representations of the data as well as meaningful models to explain patient outcomes. The tool is built to handle any type of 3D imaging data, also allowing refinements in high-resolution imaging, including histology and multiple modalities to precisely aggregate multiple data sources together.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento de Imagem Assistida por Computador / Doença de Alzheimer Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento de Imagem Assistida por Computador / Doença de Alzheimer Idioma: En Ano de publicação: 2024 Tipo de documento: Article