Primary visual cortex pathology in ALS patients with C9ORF72 expansion.

Cykowski, Matthew D; Arumanayagam, Anithachristy S; Powell, Suzanne Z; Appel, Stanley H.

Afiliação

Cykowski MD; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.
Arumanayagam AS; Department of Neurology, Houston Methodist Hospital, Houston, Texas, USA.
Powell SZ; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York, USA.
Appel SH; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.

Brain Pathol ; : e13229, 2023 Nov 27.

Article em En | MEDLINE | ID: mdl-38009843

ABSTRACT

Poly-GA and poly-GP immunofluorescence studies show conspicuous dipeptide repeat pathology in layers IV and II of primary visual cortex in C9ALS patients.

Palavras-chave

ALS; C9ORF72; TDP-43; calcium-binding protein; dipeptide repeat; visual cortex

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article