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Addition of danicopan to ravulizumab or eculizumab in patients with paroxysmal nocturnal haemoglobinuria and clinically significant extravascular haemolysis (ALPHA): a double-blind, randomised, phase 3 trial.
Lee, Jong Wook; Griffin, Morag; Kim, Jin Seok; Lee Lee, Lily Wong; Piatek, Caroline; Nishimura, Jun-Ichi; Carrillo Infante, Cynthia; Jain, Deepak; Liu, Peng; Filippov, Gleb; Sicre de Fontbrune, Flore; Risitano, Antonio; Kulasekararaj, Austin G.
Afiliação
  • Lee JW; Department of Hematology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea. Electronic address: jwlee@catholic.ac.kr.
  • Griffin M; Department of Haematology, Leeds Teaching Hospitals, Leeds, UK.
  • Kim JS; Division of Hematology, Department of Internal Medicine, Yonsei University College of Medicine, Severance Hospital, Seoul, South Korea.
  • Lee Lee LW; Hematology Unit, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysia.
  • Piatek C; University of Southern California/LAC+USC Medical Center, Los Angeles, CA, USA.
  • Nishimura JI; Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Carrillo Infante C; Alexion, AstraZeneca Rare Disease, Boston, MA, USA.
  • Jain D; Alexion, AstraZeneca Rare Disease, Boston, MA, USA.
  • Liu P; Alexion, AstraZeneca Rare Disease, Boston, MA, USA.
  • Filippov G; Alexion, AstraZeneca Rare Disease, Boston, MA, USA.
  • Sicre de Fontbrune F; Centre de Référence Aplasie Médullaire, Service d'Hématologie Greffe, Assistance Publique des Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France.
  • Risitano A; Federico II University of Naples, Naples, Italy; AORN Moscati, Avellino, Italy.
  • Kulasekararaj AG; King's College Hospital NHS Foundation Trust, NIHR/Wellcome King's Clinical Research Facility, London, UK; King's College London, London, UK.
Lancet Haematol ; 10(12): e955-e965, 2023 Dec.
Article em En | MEDLINE | ID: mdl-38030318
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colecistite / COVID-19 / Hemoglobinúria Paroxística Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colecistite / COVID-19 / Hemoglobinúria Paroxística Idioma: En Ano de publicação: 2023 Tipo de documento: Article