Your browser doesn't support javascript.
loading
Trans-cyclosulfamidate mannose-configured cyclitol allows isoform-dependent inhibition of GH47 α-d-mannosidases through a bump-hole strategy.
Males, Alexandra; Kok, Ken; Nin-Hill, Alba; de Koster, Nicky; van den Beukel, Sija; Beenakker, Thomas J M; van der Marel, Gijsbert A; Codée, Jeroen D C; Aerts, Johannes M F G; Overkleeft, Herman S; Rovira, Carme; Davies, Gideon J; Artola, Marta.
Afiliação
  • Males A; York Structural Biology Laboratory, Department of Chemistry, The University of York York YO10 5DD UK gideon.davies@york.ac.uk.
  • Kok K; Department of Medical Biochemistry, Leiden Institute of Chemistry (LIC), Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands m.e.artola@lic.leidenuniv.nl.
  • Nin-Hill A; Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica), Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona Martí i Franquès 1 08028 Barcelona Spain c.rovira@ub.edu.
  • de Koster N; Fundació Catalana de Recerca i Estudis Avançats (ICREA) Passeig Lluís Companys 23 08010 Barcelona Spain.
  • van den Beukel S; Department of Medical Biochemistry, Leiden Institute of Chemistry (LIC), Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands m.e.artola@lic.leidenuniv.nl.
  • Beenakker TJM; Department of Medical Biochemistry, Leiden Institute of Chemistry (LIC), Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands m.e.artola@lic.leidenuniv.nl.
  • van der Marel GA; Department of Bio-organic Synthesis, Leiden Institute of Chemistry (LIC), Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands.
  • Codée JDC; Department of Bio-organic Synthesis, Leiden Institute of Chemistry (LIC), Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands.
  • Aerts JMFG; Department of Bio-organic Synthesis, Leiden Institute of Chemistry (LIC), Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands.
  • Overkleeft HS; Department of Medical Biochemistry, Leiden Institute of Chemistry (LIC), Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands m.e.artola@lic.leidenuniv.nl.
  • Rovira C; Department of Bio-organic Synthesis, Leiden Institute of Chemistry (LIC), Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands.
  • Davies GJ; Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica), Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona Martí i Franquès 1 08028 Barcelona Spain c.rovira@ub.edu.
  • Artola M; Fundació Catalana de Recerca i Estudis Avançats (ICREA) Passeig Lluís Companys 23 08010 Barcelona Spain.
Chem Sci ; 14(46): 13581-13586, 2023 Nov 29.
Article em En | MEDLINE | ID: mdl-38033892
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article