Epigenetic age biomarkers and risk assessment in adult spinal deformity: a novel association of biological age with frailty and disability.

Safaee, Michael M; Dwaraka, Varun B; Lee, Justin M; Fury, Marissa; Mendez, Tavis L; Smith, Ryan; Lin, Jue; Smith, Dana L; Burke, John F; Scheer, Justin K; Went, Hannah; Ames, Christopher P

Safaee, Michael M; Dwaraka, Varun B; Lee, Justin M; Fury, Marissa; Mendez, Tavis L; Smith, Ryan; Lin, Jue; Smith, Dana L; Burke, John F; Scheer, Justin K; Went, Hannah; Ames, Christopher P.

Afiliação

Safaee MM; 1Department of Neurological Surgery, University of Southern California, Los Angeles, California.
Dwaraka VB; 2TruDiagnostic, Lexington, Kentucky.
Lee JM; Departments of3Neurological Surgery.
Fury M; Departments of3Neurological Surgery.
Mendez TL; 2TruDiagnostic, Lexington, Kentucky.
Smith R; 2TruDiagnostic, Lexington, Kentucky.
Lin J; 4Biochemistry and Biophysics, and.
Smith DL; 4Biochemistry and Biophysics, and.
Burke JF; Departments of3Neurological Surgery.
Scheer JK; Departments of3Neurological Surgery.
Went H; 2TruDiagnostic, Lexington, Kentucky.
Ames CP; Departments of3Neurological Surgery.

J Neurosurg Spine ; 40(3): 312-323, 2024 Mar 01.

Article em En | MEDLINE | ID: mdl-38039536

Assuntos

Fragilidade; Adulto; Humanos; Feminino; Idoso; Masculino; Fragilidade/genética; Estudos Retrospectivos; Complicações Pós-Operatórias/epidemiologia; Medição de Risco; Biomarcadores; Envelhecimento/genética; Epigênese Genética/genética

Palavras-chave

biological age; chronological age; deformity; epigenetics; risk assessment; spine surgery

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragilidade Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragilidade Idioma: En Ano de publicação: 2024 Tipo de documento: Article