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Co-targeting HSP90 alpha and CDK7 overcomes resistance against HSP90 inhibitors in BCR-ABL1+ leukemia cells.
Vogt, Melina; Dienstbier, Niklas; Schliehe-Diecks, Julian; Scharov, Katerina; Tu, Jia-Wey; Gebing, Philip; Hogenkamp, Julian; Bilen, Berna-Selin; Furlan, Silke; Picard, Daniel; Remke, Marc; Yasin, Layal; Bickel, David; Kalia, Munishikha; Iacoangeli, Alfredo; Lenz, Thomas; Stühler, Kai; Pandyra, Aleksandra A; Hauer, Julia; Fischer, Ute; Wagener, Rabea; Borkhardt, Arndt; Bhatia, Sanil.
Afiliação
  • Vogt M; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Dienstbier N; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Schliehe-Diecks J; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Scharov K; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Tu JW; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Gebing P; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Hogenkamp J; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Bilen BS; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Furlan S; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Picard D; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Remke M; German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Yasin L; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Bickel D; German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Kalia M; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Iacoangeli A; Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Brussels, Belgium.
  • Lenz T; Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium.
  • Stühler K; Department of Biostatistics and Health Informatics, King's College London, London, UK.
  • Pandyra AA; Department of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.
  • Hauer J; Department of Biostatistics and Health Informatics, King's College London, London, UK.
  • Fischer U; Department of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.
  • Wagener R; National Institute for Health Research Biomedical Research Centre and Dementia Unit at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.
  • Borkhardt A; Molecular Proteomics Laboratory, Biological Medical Research Center, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
  • Bhatia S; Institute for Molecular Medicine, Proteome Research, University Hospital and Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Cell Death Dis ; 14(12): 799, 2023 12 06.
Article em En | MEDLINE | ID: mdl-38057328
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Proteínas de Choque Térmico HSP90 / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Proteínas de Choque Térmico HSP90 / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article