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Intramolecular trapping of an iminium salt: rapid construction of quindoline derivatives.
Zhou, Pan; Wu, Senhui; Niu, Kaikai; Song, Hongjian; Liu, Yuxiu; Zhang, Jingjing; Wang, Qingmin.
Afiliação
  • Zhou P; State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin, 300071, People's Republic of China. songhongjian@nankai.edu.cn.
  • Wu S; State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin, 300071, People's Republic of China. songhongjian@nankai.edu.cn.
  • Niu K; State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin, 300071, People's Republic of China. songhongjian@nankai.edu.cn.
  • Song H; State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin, 300071, People's Republic of China. songhongjian@nankai.edu.cn.
  • Liu Y; State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin, 300071, People's Republic of China. songhongjian@nankai.edu.cn.
  • Zhang J; State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin, 300071, People's Republic of China. songhongjian@nankai.edu.cn.
  • Wang Q; College of Basic Science, Tianjin Agricultural University, Tianjin 300384, China.
Chem Commun (Camb) ; 60(3): 292-295, 2024 Jan 02.
Article em En | MEDLINE | ID: mdl-38059581
ABSTRACT
Construction of the pyridine ring is a practical and streamline way to construct a variety of quindoline derivatives. We have developed a novel method for synthesis of quindoline derivatives by means of intramolecular ring-closure reactions of 3-N-methylphenylindoles via an iminium salt intermediate. This practical method has the advantages of a short reaction time, operational simplicity, and nearly quantitative yields; and it can be used for the rapid synthesis of a variety of valuable quindoline derivatives.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article