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Inhibiting cholesterol de novo synthesis promotes hepatocellular carcinoma progression by upregulating prostaglandin E synthase 2-mediated arachidonic acid metabolism under high fatty acid conditions.
Zhao, Zhibo; Liu, Xinyi; Xiang, Yue; Hou, Zhengping; He, Kun; Zhong, Guochao; Hu, Jiejun; Cai, Dong; Liu, Yan; Ren, Jihua; Gong, Jianping; Zhao, Lei.
Afiliação
  • Zhao Z; Department of Hepatobiliary Surgery, Centre for Lipid Research and Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Liu X; Department of Hepatobiliary Surgery, Centre for Lipid Research and Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Xiang Y; Department of General Surgery, The People's Hospital of Jianyang City, Jianyang, China.
  • Hou Z; Department of Hepatobiliary Surgery, Centre for Lipid Research and Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • He K; Department of Hepatobiliary Surgery, Centre for Lipid Research and Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Zhong G; Department of Hepatobiliary Surgery, Centre for Lipid Research and Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Hu J; Department of Hepatobiliary Surgery, Centre for Lipid Research and Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Cai D; Department of Hepatobiliary Surgery, Centre for Lipid Research and Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Liu Y; Department of Hepatobiliary Surgery, Centre for Lipid Research and Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Ren J; Department of Hepatobiliary Surgery, Centre for Lipid Research and Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Gong J; Chengdu University of Traditional Chinese Medicine Affiliated Fifth People's hospital, Chengdu, China.
  • Zhao L; Department of Hepatobiliary Surgery, Centre for Lipid Research and Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Cancer Sci ; 115(2): 477-489, 2024 Feb.
Article em En | MEDLINE | ID: mdl-38081591
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Inibidores de Hidroximetilglutaril-CoA Redutases / Neoplasias Hepáticas Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Inibidores de Hidroximetilglutaril-CoA Redutases / Neoplasias Hepáticas Idioma: En Ano de publicação: 2024 Tipo de documento: Article