Progressive external ophthalmoplegia - A case report.
Indian J Pathol Microbiol
; 66(4): 883-885, 2023.
Article
em En
| MEDLINE
| ID: mdl-38084557
ABSTRACT
Progressive external ophthalmoplegia is a slowly progressive hereditary mitochondrial myopathy. Most mitochondrial disorders overlap clinically, enzymatically, and genetically. The most common enzyme defect is the combined deficit of complexes I and IV. Progressive external ophthalmoplegia particularly affects the extraocular muscles and is characterised by ophthalmoplegia, and bilateral ptosis. The ptosis and ophthalmoplegia is unresponsive to anticholinergics, with no effective treatment, but corrective surgery for ptosis as a palliative one. In this article, we report a rare case of a 16-year-old female with characterstic histological features consistent with progressive external ophthalmoplegia.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Oftalmoplegia
/
Oftalmoplegia Externa Progressiva Crônica
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article