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Palladium-Catalyzed Synthesis of Indanone via C-H Annulation Reaction of Aldehydes with Norbornenes.
Lu, Wen-Xiu; Mao, Jian-Gang; Xing, Jian; Tang, Hong-Yu; Liao, Jinsheng; Quan, Yao-Sheng; Lu, Zhi-Ming; Yang, Zhi-Jian; Shen, Chao.
Afiliação
  • Lu WX; School of Chemistry and Chemical Engineering, Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Jiangxi University of Science and Technology, 156 Kejia Avenue, Ganzhou 341000, P. R. China.
  • Mao JG; School of Chemistry and Chemical Engineering, Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Jiangxi University of Science and Technology, 156 Kejia Avenue, Ganzhou 341000, P. R. China.
  • Xing J; School of Chemistry and Chemical Engineering, Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Jiangxi University of Science and Technology, 156 Kejia Avenue, Ganzhou 341000, P. R. China.
  • Tang HY; School of Chemistry and Chemical Engineering, Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Jiangxi University of Science and Technology, 156 Kejia Avenue, Ganzhou 341000, P. R. China.
  • Liao J; School of Chemistry and Chemical Engineering, Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Jiangxi University of Science and Technology, 156 Kejia Avenue, Ganzhou 341000, P. R. China.
  • Quan YS; School of Chemistry and Chemical Engineering, Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Jiangxi University of Science and Technology, 156 Kejia Avenue, Ganzhou 341000, P. R. China.
  • Lu ZM; School of Chemistry and Chemical Engineering, Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Jiangxi University of Science and Technology, 156 Kejia Avenue, Ganzhou 341000, P. R. China.
  • Yang ZJ; School of Chemistry and Chemical Engineering, Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry, Jiangxi University of Science and Technology, 156 Kejia Avenue, Ganzhou 341000, P. R. China.
  • Shen C; Key Laboratory of Pollution Exposure and Health Intervention of Zhejiang Province, College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015, P. R. China.
J Org Chem ; 89(1): 784-792, 2024 Jan 05.
Article em En | MEDLINE | ID: mdl-38096498
ABSTRACT
A novel methodology for the synthesis of indanone derivates has been developed. The palladium-catalyzed annulation reaction of o-bromobenzaldehydes with norbornene derivatives is achieved through extremely concise reaction processes. The indanone skeleton was established directly via C-H activation of the aldehyde group under a mild reaction condition. This method is simple and practical, which simplified the traditional synthesis method for the rapid construction of indanone.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article