[Janus kinase inhibitors : Indications, efficacy, uses, what should be taken into account?] / Januskinaseinhibitoren : Indikationen, Wirkung, Einsatz: Was ist zu beachten?
Dermatologie (Heidelb)
; 75(3): 256-267, 2024 Mar.
Article
em De
| MEDLINE
| ID: mdl-38100043
ABSTRACT
Janus kinase inhibitors (JAKi) represent an immunomodulatory targeted therapy in various dermatoses. Throughout the past few years, JAKi have been approved for atopic dermatitis (AD), psoriasis vulgaris (PSO), alopecia areata (AA), and vitiligo. Further indications are currently under investigation. In this article the various systenic and topical JAKi used in dermatology are being presented regarding their efficacy and safety profile. A specific focus will be set on handling with safety issues including screening and control measures during treatment with JAKi. In addition, future use of JAKi in various dermatological diseases for which nowadays only insufficient therapy options are available is being discussed.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Psoríase
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Vitiligo
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Alopecia em Áreas
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Inibidores de Janus Quinases
Idioma:
De
Ano de publicação:
2024
Tipo de documento:
Article