Channelrhodopsins: From Phototaxis to Optogenetics.
Biochemistry (Mosc)
; 88(10): 1555-1570, 2023 Oct.
Article
em En
| MEDLINE
| ID: mdl-38105024
ABSTRACT
Channelrhodopsins stand out among other retinal proteins because of their capacity to generate passive ionic currents following photoactivation. Owing to that, channelrhodopsins are widely used in neuroscience and cardiology as instruments for optogenetic manipulation of the activity of excitable cells. Photocurrents generated by channelrhodopsins were first discovered in the cells of green algae in the 1970s. In this review we describe this discovery and discuss the current state of research in the field.
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Base de dados:
MEDLINE
Assunto principal:
Optogenética
/
Fototaxia
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article