Regulation of Mitochondrial Metabolism by Hepatitis B Virus.
Viruses
; 15(12)2023 11 30.
Article
em En
| MEDLINE
| ID: mdl-38140600
ABSTRACT
Mitochondria play important roles in the synthesis of ATP, the production of reactive oxygen species, and the regulation of innate immune response and apoptosis. Many viruses perturb mitochondrial activities to promote their replication and cause cell damage. Hepatitis B virus (HBV) is a hepatotropic virus that can cause severe liver diseases, including cirrhosis and hepatocellular carcinoma (HCC). This virus can also alter mitochondrial functions and metabolism to promote its replication and persistence. In this report, we summarize recent research progress on the interaction between HBV and mitochondrial metabolism, as well as the effect this interaction has on HBV replication and persistence.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Carcinoma Hepatocelular
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Hepatite B Crônica
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Hepatite B
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Neoplasias Hepáticas
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article