Mitochondrial transplantation: the advance to therapeutic application and molecular modulation.

McCully, James D; Del Nido, Pedro J; Emani, Sitaram M.

Afiliação

McCully JD; Department of Cardiac Surgery, Boston Children's Hospital, Boston, MA, United States.
Del Nido PJ; Harvard Medical School, Boston, MA, United States.
Emani SM; Department of Cardiac Surgery, Boston Children's Hospital, Boston, MA, United States.

Front Cardiovasc Med ; 10: 1268814, 2023.

Article em En | MEDLINE | ID: mdl-38162128

ABSTRACT

Mitochondrial transplantation provides a novel methodology for rescue of cell viability and cell function following ischemia-reperfusion injury and applications for other pathologies are expanding. In this review we present our methods and acquired data and evidence accumulated to support the use of mitochondrial transplantation.

Palavras-chave

heart; mitochondria; mitochondrial transplantation; proteomics; transcriptomics

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article