Angiotensin II and post-streptococcal glomerulonephritis.
Clin Exp Nephrol
; 28(5): 359-374, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-38170299
ABSTRACT
BACKGROUND:
Post-streptococcal glomerulonephritis (PSGN) is a consequence of the infection by group A beta-hemolytic streptococcus. During this infection, various immunological processes generated by streptococcal antigens are triggered, such as the induction of antibodies and immune complexes. This activation of the immune system involves both innate and acquired immunity. The immunological events that occur at the renal level lead to kidney damage with chronic renal failure as well as resolution of the pathological process (in most cases). Angiotensin II (Ang II) is a molecule with vasopressor and pro-inflammatory capacities, being an important factor in various inflammatory processes. During PSGN some events are defined that make Ang II conceivable as a molecule involved in the inflammatory processes during the disease.CONCLUSION:
This review is focused on defining which reported events would be related to the presence of this hormone in PSGN.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções Estreptocócicas
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Streptococcus pyogenes
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Angiotensina II
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Glomerulonefrite
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article