Biological activity and structural modification of isosteviol over the past 15 years.
Bioorg Chem
; 143: 107074, 2024 Feb.
Article
em En
| MEDLINE
| ID: mdl-38176378
ABSTRACT
Isosteviol is a tetracyclic diterpenoid obtained by hydrolysis of stevioside. Due to its unique molecular skeleton and extensive pharmacological activities, isosteviol has attracted more and more attention from researchers. This review summarized the structural modification, pharmacological activity and microbial transformation of isosteviol from 04/2008 to 10/2023. In addition, the research history, structural characterization, and pharmacokinetics of isosteviol were also briefly reviewed. This review aims to provide useful literature resources and inspirations for the exploration of diterpenoid drugs.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Diterpenos do Tipo Caurano
/
Diterpenos
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article