A protocol for the stereoselective synthesis of a Star of David [2]catenane.
STAR Protoc
; 5(1): 102821, 2024 Mar 15.
Article
em En
| MEDLINE
| ID: mdl-38184851
ABSTRACT
Most complex prime links exhibit inherent topological chirality, yet their high stereoinduction remains a rare occurrence. Here, we present a protocol for the stereoselective synthesis of a molecular link comprising two triple entwined rings. We describe steps for constructing the precursor circular helicate, performing ring closure metathesis, and demetallation. We also outline procedures for bio-beads separation and data analysis. This protocol holds promise for applications in molecular nanotopology. For complete details on the use and execution of this protocol, please refer to Zhang et al. (2022).1.
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1
Base de dados:
MEDLINE
Assunto principal:
Catenanos
/
Antracenos
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article