18F- FDG PET/CT in reclassifying the probable diagnosis of IE - A review.
Indian Heart J
; 76(1): 10-15, 2024.
Article
em En
| MEDLINE
| ID: mdl-38185328
ABSTRACT
In the diagnosis of infective endocarditis (IE), Modified Duke's criteria, coupled with clinical suspicion, serve as the guiding framework. For cases involving prosthetic valve endocarditis and infections affecting implantable devices, the use of metabolic imaging with 18 F-FDG PET/CT scans has gained prominence, as per the recommendations of the European Society of Cardiology guidelines. This imaging modality enhances sensitivity and specificity by identifying infective foci within the heart and extracardiac locations. Early utilization of these scans is crucial for confirming or ruling out IE, although caution is required to mitigate false positive responses, especially in the presence of ongoing inflammatory activity. A standardized ratio of ≥2.0 between FDG uptake around infected tissues and the blood pool has demonstrated a sensitivity of 100 % and specificity of 91 %. It is noteworthy that the sensitivity of FDG PET/CT varies, being lower for native valve and lead infections but considerably higher for prosthetic valve and pulse generator infections. This review provides a comprehensive overview of the advantages offered by FDG PET/CT in achieving a definitive diagnosis of IE.
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Base de dados:
MEDLINE
Assunto principal:
Próteses Valvulares Cardíacas
/
Infecções Relacionadas à Prótese
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Endocardite
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Endocardite Bacteriana
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article