New caffeoyl derivatives with potent DPPH radical scavenging activity from Elephantopus tomentosus.
J Asian Nat Prod Res
; 26(1): 26-37, 2024 Jan.
Article
em En
| MEDLINE
| ID: mdl-38196236
ABSTRACT
Eight new caffeoyl derivatives, elephantomentosides A-H (1 - 8), together with ten known ones (9 - 18), were isolated from the whole plant of Elephantopos tomentosus L. Their structures were elucidated using detailed spectroscopic analysis. Structurally, compounds 1 - 8 are composed of ß-D-glucopyranose, and almost all of the substituent positions are at the C-1' and C-4' of glucopyranose. The anti-inflammatory and antioxidant activities of all isolated compounds were evaluated in vitro. Compounds 9-10, 13-15, and 17-18 exhibited significant DPPH scavenging capacity with IC50 values in the range of 10.01-25.07 µM, in comparison with Vc (IC50, 17.98 µM).
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Base de dados:
MEDLINE
Assunto principal:
Asteraceae
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Antioxidantes
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article