Esophageal Endoscopic Submucosal Dissection in Older Patients Is Safe and Feasible: A Retrospective Single-Center Cohort Study in the United States.
J Clin Med
; 13(1)2023 Dec 30.
Article
em En
| MEDLINE
| ID: mdl-38202236
ABSTRACT
BACKGROUND:
Endoscopic submucosal dissection (ESD) is a well-established method for treating early esophageal carcinomas. However, data on the safety and efficacy of esophageal ESD in older patients in the United States are limited.METHODS:
This retrospective study investigated the outcomes of esophageal ESD in patients aged ≥80 years and included those who underwent esophageal ESD between June 2018 and April 2023 at a single center in the United States. Patients were divided into two age groups for comparison ≥80 and <80 years. Treatment outcomes and complications were evaluated and compared between these groups.RESULTS:
A total of 53 cases of esophageal ESD for malignant neoplasms were included, with 12 patients in the ≥80 years age group. No significant differences were observed in the patients' background and characteristics, except for a prior history of interventions (p = 0.04). The en bloc resection rate was 100% in both groups. The R0 resection rate was lower in the ≥80 years age group (75% vs. 88%). There were no complications requiring additional intervention in the ≥80 years age group, such as post-ESD bleeding, perforation, mediastinal emphysema, or pneumonia.CONCLUSIONS:
Esophageal ESD may be a safe and feasible procedure for treating esophageal carcinomas in older patients.
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MEDLINE
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En
Ano de publicação:
2023
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Article