A new experimental evidence-weighted signaling pathway resource in FlyBase.
Development
; 151(3)2024 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-38230566
ABSTRACT
Research in model organisms is central to the characterization of signaling pathways in multicellular organisms. Here, we present the comprehensive and systematic curation of 17 Drosophila signaling pathways using the Gene Ontology framework to establish a dynamic resource that has been incorporated into FlyBase, providing visualization and data integration tools to aid research projects. By restricting to experimental evidence reported in the research literature and quantifying the amount of such evidence for each gene in a pathway, we captured the landscape of empirical knowledge of signaling pathways in Drosophila.
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Base de dados:
MEDLINE
Assunto principal:
Bases de Dados Genéticas
/
Drosophila
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article