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Complete Genome Sequence of the Itraconazole Decreased Susceptible Madurella fahalii Type-Strain CBS 129176.
Konings, Mickey; Gerrits van den Ende, Bert; Raats, Mirthe W J; Fahal, Ahmed Hassan; van de Sande, Wendy W J; Hagen, Ferry.
Afiliação
  • Konings M; Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
  • Gerrits van den Ende B; Department of Medical Mycology, Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands.
  • Raats MWJ; Department of Medical Mycology, Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands.
  • Fahal AH; The Mycetoma Research Center, University of Khartoum, Khartoum, Sudan.
  • van de Sande WWJ; Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. w.vandesande@erasmusmc.nl.
  • Hagen F; Department of Medical Mycology, Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands.
Mycopathologia ; 189(1): 6, 2024 Jan 17.
Article em En | MEDLINE | ID: mdl-38231295
ABSTRACT
Madurella fahalii is a causative agent of the implantation mycosis mycetoma with decreased susceptibility to itraconazole, the preferred therapeutic drug to combat mycetoma. Here, we report the M. fahalii type-strain CBS 129176 genome assembly and annotation to identify a glutamic acid insert near the azole-binding pocket in the Cyp51A protein.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Madurella / Micetoma Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Madurella / Micetoma Idioma: En Ano de publicação: 2024 Tipo de documento: Article