Clinical Characteristics of Microcystic Macular Edema in Chronic Primary Angle-Closure Glaucoma and Primary Open-Angle Glaucoma Patients.
Ophthalmic Res
; 67(1): 145-153, 2024.
Article
em En
| MEDLINE
| ID: mdl-38246159
ABSTRACT
INTRODUCTION:
This study investigated the clinical characteristics of and risk factors for microcystic macular edema (MME) in patients with chronic primary angle-closure glaucoma (CPACG) and primary open-angle glaucoma (POAG).METHODS:
This retrospective observational study included 1,588 eyes from 926 glaucoma inpatients and analyzed the patients' basic demographic information, visual field parameters, macular scans, and peripapillary retinal nerve fiber layer thickness.RESULTS:
Our findings were that the incidence rate of MME was 3.97% (34/857) in CPACG and 5.88% (43/731) in POAG. MME was predominantly diagnosed at an advanced stage in CPACG (almost 100%) compared to POAG (93.02%). MME was most frequently involved in the inferior (83.12%) quadrant of the peri-macular region in both CPACG and POAG. Risk factors for MME occurrence in CPACG and POAG included lower visual field mean deviation (OR = 1.14, 95% CI 1.05-1.24, p = 0.003; OR = 1.14, 95% CI 1.06-1.21, p < 0.001) and younger age (OR = 0.92, 95% CI 0.88-0.96, p < 0.001; OR = 0.96, 95% CI 0.93-0.99, p = 0.003), while female sex (OR = 0.30, 95% CI 0.11-0.84, p = 0.022) reduced the MME occurrence in POAG.CONCLUSION:
MME could develop in both CPACG and POAG patients, occurring earlier in POAG. The inferior peri-macular region is commonly affected. Younger age and poorer visual field are risk factors for MME in glaucoma patients.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Campos Visuais
/
Glaucoma de Ângulo Fechado
/
Glaucoma de Ângulo Aberto
/
Edema Macular
/
Tomografia de Coerência Óptica
/
Pressão Intraocular
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article