Simultaneous Electrochemical Detection of Dopamine and Uric Acid via Au@Cu-Metal Organic Framework.
Chempluschem
; 89(5): e202300686, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-38261267
ABSTRACT
The incorporation of noble metals with metal-organic frameworks (MOFs) are conducive to the simultaneous electrochemical detection of analytes owing to multiple accessible reaction sites. Herein, Au@Cu-metal organic framework (Au@Cu-MOF) is successfully synthesized and modified as a screen-printed carbon electrode (SPCE), which serves as an excellent electrocatalyst for the oxidation of dopamine (DA) and uric acid (UA). The sensor shows a linear range from 10â
µM to 1000â
µM, with sensitivity and detection limit of 0.231â
µA µM-1 cm-2 and 3.40â
µM for DA, and 0.275â
µA µM-1 cm-2 and 10.36â
µM for UA. Au@Cu-MOF could realize the individual and simultaneous electrochemical sensing of DA and UA, with distinguishable oxidation peak potentials. Moreover, it exhibits reproducibility, repeatability, and stability. Ultimately, the sensor provides an avenue for an ultrasensitive label-free electrochemical detection of DA and UA.
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Base de dados:
MEDLINE
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En
Ano de publicação:
2024
Tipo de documento:
Article