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Tissue-specific early and late activated lymphocytes immunophenotype in chronic rhinosinusitis with nasal polyps.
López-Enríquez, Soledad; Porras-González, Cristina; Moreno-Luna, Ramón; Palomares, Francisca; Muñoz-Bravo, José Luis; Alba, Gonzalo; Santa-María, Consuelo; Maza-Solano, Juan; Martín-Jiménez, Daniel Iván; Pérez-Pérez, Antonio; Moreno-Luna, Rafael; Sánchez-Margalet, Víctor; Sánchez-Gómez, Serafín.
Afiliação
  • López-Enríquez S; Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, Virgen Macarena University Hospital, Universidad de Sevilla, Seville, Spain.
  • Porras-González C; Institute of Biomedicine of Seville (IBiS)/Virgen del Rocío University Hospital/Virgen Macarena University Hospital/University of Seville/CSIC, Seville, Spain.
  • Moreno-Luna R; Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, Virgen Macarena University Hospital, Universidad de Sevilla, Seville, Spain.
  • Palomares F; Institute of Biomedicine of Seville (IBiS)/Virgen del Rocío University Hospital/Virgen Macarena University Hospital/University of Seville/CSIC, Seville, Spain.
  • Muñoz-Bravo JL; Institute of Biomedicine of Seville (IBiS)/Virgen del Rocío University Hospital/Virgen Macarena University Hospital/University of Seville/CSIC, Seville, Spain.
  • Alba G; Rhinology Unit, Department of Otolaryngology, Head and Neck Surgery, Virgen Macarena University Hospital/FISEVI, Seville, Spain.
  • Santa-María C; Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, Virgen Macarena University Hospital, Universidad de Sevilla, Seville, Spain.
  • Maza-Solano J; Institute of Biomedicine of Seville (IBiS)/Virgen del Rocío University Hospital/Virgen Macarena University Hospital/University of Seville/CSIC, Seville, Spain.
  • Martín-Jiménez DI; Clinical Analysis Service, General University Hospital of Elche, Foundation for the Promotion of Health and Biomedical Research in the Valencia Region (FISABIO), Elche, Spain.
  • Pérez-Pérez A; Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, Virgen Macarena University Hospital, Universidad de Sevilla, Seville, Spain.
  • Moreno-Luna R; Department of Biochemistry and Molecular Biology, School of Pharmacy, Universidad de Sevilla, Seville, Spain.
  • Sánchez-Margalet V; Institute of Biomedicine of Seville (IBiS)/Virgen del Rocío University Hospital/Virgen Macarena University Hospital/University of Seville/CSIC, Seville, Spain.
  • Sánchez-Gómez S; Rhinology Unit, Department of Otolaryngology, Head and Neck Surgery, Virgen Macarena University Hospital/FISEVI, Seville, Spain.
Int Forum Allergy Rhinol ; 14(7): 1245-1248, 2024 Jul.
Article em En | MEDLINE | ID: mdl-38268107
ABSTRACT
KEY POINTS T-cell activation in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) is enriched by late cytotoxic T cells. The proportion of early and intermediate activated cytotoxic T cells decreases in nasal polyps of patients with CRSwNP. Our results identify late activated cytotoxic T cells as potential biomarkers or therapeutic targets for patients with CRSwNP.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sinusite / Ativação Linfocitária / Rinite / Pólipos Nasais / Imunofenotipagem Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sinusite / Ativação Linfocitária / Rinite / Pólipos Nasais / Imunofenotipagem Idioma: En Ano de publicação: 2024 Tipo de documento: Article