Comparison of quantification of intraretinal hard exudates between optical coherence tomography en face image versus fundus photography.
Indian J Ophthalmol
; 72(Suppl 2): S280-S296, 2024 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-38271424
ABSTRACT
PURPOSE:
To compare the quantification of intraretinal hard exudate (HE) using en face optical coherence tomography (OCT) and fundus photography.METHODS:
Consecutive en face images and corresponding fundus photographs from 13 eyes of 10 patients with macular edema associated with diabetic retinopathy or Coats' disease were analyzed using the machine-learning-based image analysis tool, "ilastik."RESULTS:
The overall measured HE area was greater with en face images than with fundus photos (en face 0.49 ± 0.35 mm2 vs. fundus photo 0.34 ± 0.34 mm2, P < 0.001). However, there was an excellent correlation between the two measurements (intraclass correlation coefficient [ICC] = 0.844). There was a negative correlation between HE area and central macular thickness (CMT) (r = -0.292, P = 0.001). However, HE area showed a positive correlation with CMT in the previous several months, especially in eyes treated with anti-vascular endothelial growth factor (VEGF) therapy (CMT 3 months before r = 0.349, P = 0.001; CMT 4 months before r = 0.287, P = 0.012).CONCLUSION:
Intraretinal HE can be reliably quantified from either en face OCT images or fundus photography with the aid of an interactive machine learning-based image analysis tool. HE area changes lagged several months behind CMT changes, especially in eyes treated with anti-VEGF injections.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tomografia de Coerência Óptica
/
Retinopatia Diabética
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article