11ß Hydroxylase Deficiency in a Child with Hypothyroidism: A Case Report.

ABSTRACT

Congenital adrenal hyperplasia occurs due to enzymatic defects in the adrenocortical steroidogenesis. 11ß hydroxylase deficiency is the second most common cause of congenital adrenal hyperplasia which presents with hypertension and features of androgen excess. Hypertension has also been found to cause end-organ damage in children with 11ß hydroxylase deficiency. We report a case of a 10-year-old male child with hypothyroidism under thyroid replacement therapy, presenting with features of severe hypertension and androgen excess, later on, diagnosed as congenital adrenal hyperplasia due to 11ß hydroxylase deficiency. Keywords case reports; congenital adrenal hyperplasia; hypertension; hypothyroidism.