Clinical practices and adherence to guidelines for eosinophilic esophagitis: A European survey.
Dig Liver Dis
; 56(7): 1196-1203, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38290961
ABSTRACT
BACKGROUND:
We aimed to assess the clinical practices and adherence to guidelines for adult Eosinophilic Esophagitis (EoE) patients in Europe.METHODS:
A cross-sectional web survey containing 23 questions was distributed to members of the European Consortium for Eosinophilic Diseases of the Gastrointestinal Tract (EUREOS) and the Italian Association of Hospital Gastroenterologists and digestive endoscopists (AIGO). We conducted a subgroup analysis to assess the impact of EoE expertise and practice setting on clinical practices.RESULTS:
228 physicians from 18 European countries participated. Adherence to guidelines varied from 72% to 98.6%. 83.4% of total respondents obtained ≥ 6 esophageal biopsies in suspected EoE. 42% of total respondents, 82.5% of EoE experts (vs. non-experts 33%; P < 0.0001), and 55% of academics (vs. 29.1 non-academics; P < 0.0001) routinely used the EREFS score. Regarding first-line therapy, 82.9% of total respondents prescribed proton pump inhibitors, 41.6% topical steroids, 20.6% elimination diets, and 9.2% combination therapies. Only 72% of respondents used symptoms and endoscopy with <15 Eosinophils/HPF to define treatment response. 21.5% of all respondents did not prescribe maintenance therapies and 12.7% discontinued therapy before response evaluation endoscopy.CONCLUSION:
Our findings revealed significant heterogeneity in practice patterns and suboptimal adherence to EoE guidelines across Europe. Expertise in EoE and working in an academic hospital positively influenced clinical practices and adherence to guidelines.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Padrões de Prática Médica
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Guias de Prática Clínica como Assunto
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Fidelidade a Diretrizes
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Inibidores da Bomba de Prótons
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Esofagite Eosinofílica
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article