Biology and physiology of tendon healing.
Joint Bone Spine
; 91(5): 105696, 2024 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-38307405
ABSTRACT
Tendon disorders affect people of all ages, from elite and recreational athletes and workers to elderly patients. After an acute injury, 3 successive phases are described to achieve healing an inflammatory phase followed by a proliferative phase, and finally by a remodeling phase. Despite this process, healed tendon fails to recover its original mechanical properties. In this review, we proposed to describe the key factors involved in the process such as cells, transcription factors, extracellular matrix components, cytokines and growth factors and vascularization among others. A better understanding of this healing process could help provide new therapeutic approaches to improve patients' recovery while tendon disorders management remains a medical challenge.
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MEDLINE
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En
Ano de publicação:
2024
Tipo de documento:
Article