An interdisciplinary course on computer-aided drug discovery to broaden student participation in original scientific research.
Biochem Mol Biol Educ
; 52(3): 276-290, 2024.
Article
em En
| MEDLINE
| ID: mdl-38308532
ABSTRACT
We present a new highly interdisciplinary project-based course in computer aided drug discovery (CADD). This course was developed in response to a call for alternative pedagogical approaches during the COVID-19 pandemic, which caused the cancellation of a face-to-face summer research program sponsored by the Louisiana Biomedical Research Network (LBRN). The course integrates guided research and educational experiences for chemistry, biology, and computer science students. We implement research-based methods with publicly available tools in bioinformatics and molecular modeling to identify and prioritize promising antiviral drug candidates for COVID-19. The purpose of this course is three-fold I. Implement an active learning and inclusive pedagogy that fosters student engagement and research mindset; II. Develop student interdisciplinary research skills that are highly beneficial in a broader scientific context; III. Demonstrate that pedagogical shifts (initially incurred during the COVID-19 pandemic) can furnish longer-term instructional benefits. The course, which has now been successfully taught a total of five times, incorporates four modules, including lectures/discussions, live demos, inquiry-based assignments, and science communication.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Estudantes
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Descoberta de Drogas
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SARS-CoV-2
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COVID-19
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article