Role of IgG avidity in eyes with active Toxoplasma retinochoroiditis.
Indian J Ophthalmol
; 72(Suppl 4): S601-S605, 2024 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-38324620
ABSTRACT
PURPOSE:
To study the role of Toxoplasma IgG avidity in evaluating the stage of systemic infection during manifestation as toxoplasma retinochoroiditis and its clinical implications in eastern India.METHODS:
Retrospective chart review of Toxoplasma retinochoroiditis cases with Toxoplasma serology for IgG, IgM, and IgG avidity.RESULTS:
Included in this study were 17 eyes of 17 patients who had active retinitis located in the macula (14), mid-periphery (2), or periphery (1). They were either primary lesions (12) or reactivations (5). All the cases had Toxoplasma IgG positive; one case had IgM positivity, while all the cases had high IgG avidity values. IgG avidity had a positive correlation with the duration of symptoms.CONCLUSION:
We observed high IgG avidity values in active retinochoroiditis in both primary ocular Toxoplasmosis and reactivation subgroups. These results indicate a late ocular manifestation after initial systemic infection with a possible incubation period ranging from 5 weeks to 5 months.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Toxoplasma
/
Imunoglobulina G
/
Anticorpos Antiprotozoários
/
Toxoplasmose Ocular
/
Coriorretinite
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article