A Comprehensive Review of the Diverse Spectrum Activity of 1,2,3-Triazole-linked Isatin Hybrids.
Chem Biodivers
; 21(4): e202301612, 2024 Apr.
Article
em En
| MEDLINE
| ID: mdl-38332679
ABSTRACT
Heterocyclic compounds containing 1,2,3-triazole and isatin as core structures have emerged as promising drug candidates due to their diverse biological activities such as anti-cancer, antifungal, antimicrobial, antitumor, anti-epileptic, antiviral, and more. The presence of 1,2,3-triazoles and isatin heterocycles in these hybrids, both individually known for their medicinal significance, has increasingly piqued the interest of drug discovery researchers, as they seek to delve deeper into their extensive pharmacological potential for enhancing therapeutic efficacy. Moreover, these hybrid compounds are synthetically accessible using readily available materials. Therefore, there is a pressing need to provide a comprehensive overview of the existing knowledge in this field, offering valuable insights to readers and paving the way for the discovery of novel 1,2,3-triazole-linked isatin hybrids with therapeutic potential.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Isatina
/
Anti-Infecciosos
/
Neoplasias
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article