Life's Essential 8, Life's Simple 7 and the odds of hyperuricaemia: results from the China Multi-Ethnic Cohort Study.

Wang, Yanjiao; Meng, Qiong; Zhang, Xuehui; Baima, Kangzhuo; Chen, Liling; Dai, Yingxue; Yang, Tingting; Feng, Yuemei; Mi, Fei; Zhou, Junmin; Yin, Jianzhong

Wang, Yanjiao; Meng, Qiong; Zhang, Xuehui; Baima, Kangzhuo; Chen, Liling; Dai, Yingxue; Yang, Tingting; Feng, Yuemei; Mi, Fei; Zhou, Junmin; Yin, Jianzhong.

Afiliação

Wang Y; School of Public Health, Kunming Medical University, Kunming, China.
Meng Q; School of Public Health, Kunming Medical University, Kunming, China.
Zhang X; School of Public Health, Kunming Medical University, Kunming, China.
Baima K; High Altitude Health Science Research Center of Xizang University, Lhasa, Xizang, China.
Chen L; National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Dai Y; Institute of Chronic Non-Communicable Disease Control and Prevention, Chongqing Center for Disease Control and Prevention, Chongqing, China.
Yang T; Chengdu Center for Disease Control and Prevention, Chengdu, China.
Feng Y; School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, China.
Mi F; School of Public Health, Kunming Medical University, Kunming, China.
Zhou J; School of Public Health, Kunming Medical University, Kunming, China.
Yin J; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.

Rheumatol Adv Pract ; 8(1): rkae009, 2024.

Article em En | MEDLINE | ID: mdl-38333884

ABSTRACT

ABSTRACT

Objective:

Life's Essential 8 (LE8) is a new comprehensive metric based on Life's Simple 7 (LS7). Few studies have investigated the association between LE8 and the odds of hyperuricaemia (HUA). This study examined the association between LE8, LS7 with odds of HUA.

Methods:

We cross-sectionally analysed data from the China Multi-Ethnic Cohort (CMEC) study. LE8 and LS7 were categorized as low, moderate and high. The CMEC provided an ideal and unique opportunity to characterize the association between LE8, LS7 and the odds of HUA.

Results:

Of the 89 823 participants, 14 562 (16.2%) had HUA. A high level of LE8 was associated with lower odds of HUA after full adjustment. The adjusted odds ratios (ORs) were 1 (reference), 0.70 (95% CI 0.67, 0.73) and 0.45 (0.42, 0.48) across low, moderate and high LE8 groups, respectively (Ptrend < 0.001). Similar results were observed in LS7 and HUA. The adjusted ORs were 1 (reference), 0.68 (95% CI 0.65, 0.71) and 0.46 (95% CI 0.43, 0.49) across low, moderate and high LS7 groups, respectively (Ptrend < 0.001). There were significant interactions between LE8 and age, gender, ethnicity and drinking habits on HUA. Receiver operating characteristics analysis showed that the area under the curve for LE8 and LS7 were similar (0.638 and 0.635, respectively).