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Current Treatment and Immunomodulation Strategies in Acute Myocarditis.
Ferone, Emma; Segev, Amitai; Tempo, Erika; Gentile, Piero; Elsanhoury, Ahmed; Baggio, Chiara; Artico, Jessica; Bhatti, Prashan; Scott, Paul; Bobbio, Emanuele; Merlo, Marco; Ameri, Pietro; Sinagra, Gianfranco; Tschöpe, Carsten; Bromage, Daniel; Cannata, Antonio.
Afiliação
  • Ferone E; School of Cardiovascular Medicine and Sciences, King's College London, London, United Kingdom.
  • Segev A; Cardiovascular Division, Chaim Sheba Medical Center, Tel Hashomer, Ramat-Gan, Israel.
  • Tempo E; The Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
  • Gentile P; Department of Internal Medicine, University of Genova, Genova, Italy.
  • Elsanhoury A; Ospedale Niguarda Ca'granda, Milan, Italy.
  • Baggio C; Berlin Institute of Health (BIH) Center for Regenerative Therapies (BCRT), Berlin, Germany.
  • Artico J; Department of Cardiology, Angiology, and Intensive Medicine (CVK), German Heart Center at Charite (DHZC), Berlin, Germany.
  • Bhatti P; German Centre for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany.
  • Scott P; CardioThoracoVascular Department, Azienda Sanitaria Universitaria Giuliano-Isontina, Trieste, Italy.
  • Bobbio E; Department of Cardiology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Merlo M; Institute of Cardiovascular Science, University College London, London, United Kingdom.
  • Ameri P; School of Cardiovascular Medicine and Sciences, King's College London, London, United Kingdom.
  • Sinagra G; King's College Hospital NHS Foundation Trust, London, United Kingdom.
  • Tschöpe C; King's College Hospital NHS Foundation Trust, London, United Kingdom.
  • Bromage D; Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Cannata A; Department of Molecular and Clinical Medicine, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
J Cardiovasc Pharmacol ; 83(5): 364-376, 2024 05 01.
Article em En | MEDLINE | ID: mdl-38335530
ABSTRACT
ABSTRACT Myocarditis is an inflammatory disease of the myocardium characterized by a great heterogeneity of presentation and evolution. Treatment of myocarditis is often supportive, and the evidence for immunosuppression is scarce and debated. Conventional treatment is based on clinical presentation, ranging from conservative to advanced mechanical assist devices. In this setting, immunosuppression and immunomodulation therapies are mostly reserved for patients presenting with major clinical syndromes. In this review, we will summarize the current evidence and strategies for conventional and immunosuppressive treatments for patients presenting with acute myocarditis.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunossupressores / Miocardite Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunossupressores / Miocardite Idioma: En Ano de publicação: 2024 Tipo de documento: Article