Safety and efficacy of ovarian tissue autotransplantation: A systematic literature review.
Folia Med (Plovdiv)
; 65(3): 362-370, 2023 Jun 30.
Article
em En
| MEDLINE
| ID: mdl-38351810
ABSTRACT
Ovarian tissue autotransplantation is an innovative fertility preservation technique that has provoked ongoing investigations. The purpose of the present study was to assess the safety and reproductive performance of ovarian tissue autotransplantation. This review is conducted according to PRISMA guidelines. Seven studies met the inclusion criteria. A total of 3427 patients underwent ovarian tissue cryopreservation and 205 received an autotransplantation. Tissue retrieval was mainly performed by laparoscopy and only one major complication occurred. Transplantations were predominantly performed by open procedures and data on safety were insufficient. A total of 295 autotransplantations were analyzed, resulting in 104 pregnancies. Sixty-five pregnancies led to live births, while nine were ongoing at that time. A pregnancy rate (PR) of 50.7% and a live-birth rate (LBR) of 32.7% were observed. Natural conception accounted for 46.3% of live births. No birth deficits were recorded. Ovarian tissue autotransplantation seems to be a safe procedure with acceptable pregnancy rates.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ovário
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Transplante Autólogo
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Criopreservação
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Preservação da Fertilidade
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article