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A perspective current and past modes of inhalation therapy.
Canto Mangana, José; Schilder, Kelsey Aguirre; Bretones-Pedrinaci, José Ignacio; Blesa, Ana Rosa Márquez; de Medina, Fermín Sánchez; Martínez-Augustin, Olga; Daddaoua, Abdelali.
Afiliação
  • Canto Mangana J; Department of Biochemistry and Molecular Biology II, Pharmacy School, University of Granada, Granada, Spain.
  • Schilder KA; Pharmacy Services, A.S. Hospital de Poniente de Almería, Almería, Spain.
  • Bretones-Pedrinaci JI; Department of Biochemistry and Molecular Biology II, Pharmacy School, University of Granada, Granada, Spain.
  • Blesa ARM; Pharmacy Services, A.S. Hospital de Poniente de Almería, Almería, Spain.
  • de Medina FS; Department of Biochemistry and Molecular Biology II, Pharmacy School, University of Granada, Granada, Spain.
  • Martínez-Augustin O; Department of Pharmacology, School of Pharmacy, University of Granada, Granada, Spain.
  • Daddaoua A; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.
Microb Biotechnol ; 17(2): e14419, 2024 Feb.
Article em En | MEDLINE | ID: mdl-38387963
ABSTRACT
Inhalation is the preferred route of delivery for anti-asthma and chronic obstructive pulmonary disease (COPD) drugs. The use of this route has demonstrated efficacy in these and other conditions, it offers rapid onset of action, and is associated with minimal systemic exposure, thereby reducing the risk of adverse effects. Therefore, the current brief covers an interesting collection of inhaler action modes, shedding light on their molecular mechanisms and clinical applications for anti-asthma, COPD and antibacterial inhalation therapy. Hence, not only enriches our understanding of inhalation therapy molecular intricacies but also provides a comprehensive overview of the evolving landscape in clinical and antibacterial inhalation therapy. In doing so, it underscores the pivotal role of microbiology and biotechnology in advancing therapeutic approaches that harness the power of inhalation.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Administração por Inalação / Nebulizadores e Vaporizadores / Doença Pulmonar Obstrutiva Crônica Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Administração por Inalação / Nebulizadores e Vaporizadores / Doença Pulmonar Obstrutiva Crônica Idioma: En Ano de publicação: 2024 Tipo de documento: Article