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A non-peptide-based fluorescent probe capable of sensitively visualizing asparagine endopeptidase.
Li, Kang; Hou, Yanxian; Han, Jinliang; Lv, Chengyuan; Liu, Wenkai; Du, Jianjun; Sun, Wen; Fan, Jiangli; Peng, Xiaojun.
Afiliação
  • Li K; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. fanjl@dlut.edu.cn.
  • Hou Y; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. fanjl@dlut.edu.cn.
  • Han J; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. fanjl@dlut.edu.cn.
  • Lv C; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. fanjl@dlut.edu.cn.
  • Liu W; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. fanjl@dlut.edu.cn.
  • Du J; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. fanjl@dlut.edu.cn.
  • Sun W; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. fanjl@dlut.edu.cn.
  • Fan J; State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China. fanjl@dlut.edu.cn.
  • Peng X; Ningbo Institute of Dalian University of Technology, Ningbo 315016, China.
Chem Commun (Camb) ; 60(22): 3031-3034, 2024 Mar 12.
Article em En | MEDLINE | ID: mdl-38391081
ABSTRACT
The non-peptide-based fluorescent probe QMC11 is capable of specifically targeting asparagine endopeptidase (AEP) and imaging cellular endogenous AEP. The motion of the probe can be restricted by AEP to activate fluorescence while keeping a low background signal.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cisteína Endopeptidases / Corantes Fluorescentes Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cisteína Endopeptidases / Corantes Fluorescentes Idioma: En Ano de publicação: 2024 Tipo de documento: Article