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Indications, Techniques and Future Perspectives of Walled-off Necrosis Management.
Troncone, Edoardo; Amendola, Rosa; Gadaleta, Fabio; De Cristofaro, Elena; Neri, Benedetto; De Vico, Pasquale; Paoluzi, Omero Alessandro; Monteleone, Giovanni; Anderloni, Andrea; Del Vecchio Blanco, Giovanna.
Afiliação
  • Troncone E; Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
  • Amendola R; Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
  • Gadaleta F; Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
  • De Cristofaro E; Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
  • Neri B; Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
  • De Vico P; Department of Anaesthesia, University of Rome "Tor Vergata", 00133 Rome, Italy.
  • Paoluzi OA; Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
  • Monteleone G; Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
  • Anderloni A; Endoscopy Unit, First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, 27029 Pavia, Italy.
  • Del Vecchio Blanco G; Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Diagnostics (Basel) ; 14(4)2024 Feb 09.
Article em En | MEDLINE | ID: mdl-38396420
ABSTRACT
Necrotizing pancreatitis is a complex clinical condition burdened with significant morbidity and mortality. In recent years, the huge progress of interventional endoscopic ultrasound (EUS) has allowed a shift in the management of pancreatic necrotic collections from surgical/percutaneous approaches to mini-invasive endoscopic internal drainage and debridement procedures. The development of lumen-apposing metal stents (LAMSs), devices specifically dedicated to transmural EUS interventions, further prompted the diffusion of such techniques. Several studies have reported excellent outcomes of endoscopic interventions, in terms of technical success, clinical efficacy and safety compared to surgical interventions, and thus endoscopic drainage of walled-off necrosis (WON) has become a fundamental tool for the management of such conditions. Despite these advancements, some critical unresolved issues remain. Endoscopic therapeutic approaches to WON are still heterogeneous among different centers and experts. A standardized protocol on indication, timing and technique of endoscopic necrosectomy is still lacking, and experts often adopt a strategy based on personal experience more than robust data from well-conducted studies. In this review, we will summarize the available evidence on endoscopic management of WON and will discuss some unanswered questions in this rapidly evolving field.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article