A case of benign immunoglobulin D monoclonal gammopathy of undetermined significance with 26 years of follow-up.
EJHaem
; 5(1): 235-237, 2024 Feb.
Article
em En
| MEDLINE
| ID: mdl-38406530
ABSTRACT
The presence of a serum immunoglobulin D (IgD) monoclonal protein (M-protein) is seen in < 1% of patients with monoclonal gammopathies and is usually indicative of a malignant plasma cell disorder. Only a few cases of well-documented benign monoclonal gammopathy of undetermined significance (MGUS) of IgD subtype have been reported, and only 2 of those had over 5 years of follow-up at the time they were reported. Herein we describe longer-term follow-up of one of those 2 patients who has subsequently passed away from unrelated causes but never developed multiple myeloma or amyloidosis after 26 years of follow-up. Although IgD MGUS is extremely rare, this case confirms that presence of an IgD M-Protein is not always synonymous with a malignant plasma cell process.
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MEDLINE
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En
Ano de publicação:
2024
Tipo de documento:
Article