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Children had increased risks of impaired motor and visual-motor skills after prenatal exposure to opioid maintenance therapy.
Aslaksen, Anne Kathinka; Hoem, Mari Leirdal; Vikesdal, Gro Horgen; Voie, Marit Torbergsen; Haugen, Olav H; Skranes, Jon.
Afiliação
  • Aslaksen AK; Department of Pediatrics, Sørlandet Hospital, Kristiansand, Norway.
  • Hoem ML; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.
  • Vikesdal GH; Department of Clinical Medicine K1, Faculty of Medicine, University of Bergen, Bergen, Norway.
  • Voie MT; Department of Pediatrics, Sørlandet Hospital, Arendal, Norway.
  • Haugen OH; Department of Optometry, Radiography and Lighting Design, University of South-Eastern Norway, Kongsberg, Norway.
  • Skranes J; Department of Ophthalmology, Sørlandet Hospital, Arendal, Norway.
Acta Paediatr ; 113(6): 1331-1339, 2024 06.
Article em En | MEDLINE | ID: mdl-38415880
ABSTRACT

AIM:

Preschool children prenatally exposed to opioid maintenance therapy (OMT) have an increased risk of neurodevelopmental impairments. We aimed to investigate long-term motor and visual-motor integration outcome in children aged 5-13 Years, born to mothers in OMT.

METHODS:

From January 2018 to June 2021, 63 children prenatally exposed to OMT and 63 comparison children matched for age and gender, were examined at two Norwegian hospitals. Motor skills were assessed by the Movement-ABC test and visual-motor integration by the Beery VMI test. A motor function neurological assessment test was used to examine neuromotor soft signs.

RESULTS:

In the OMT-exposed group, 16% had motor impairment, 35% had motor problems and 19% had visual-motor integration problems. Forty-three percent of the exposed children had neuromotor soft signs. Strabismus had some influence on motor and visual-motor outcomes but could not explain the group differences.

CONCLUSION:

Children prenatally exposed to opioid maintenance therapy have an increased risk of long-term motor impairment and visual-motor problems. In addition, they exhibit significantly more neuromotor soft signs, which may affect general well-being, leisure activities and school performance.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Efeitos Tardios da Exposição Pré-Natal / Tratamento de Substituição de Opiáceos Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Efeitos Tardios da Exposição Pré-Natal / Tratamento de Substituição de Opiáceos Idioma: En Ano de publicação: 2024 Tipo de documento: Article