STEC colitis mimicking acute severe colitis with life-threatening consequences: a case report.
Acta Gastroenterol Belg
; 87(1): 37-39, 2024.
Article
em En
| MEDLINE
| ID: mdl-38431789
ABSTRACT
Acute colitis is a common feature of infection with Shiga-toxin producing Escherichia coli (STEC) and can mimic acute severe ulcerative colitis. Early recognition is important as there is a risk of developing Shiga toxin-induced haemolytic uremic syndrome (STEC-HUS), defined by the triad of microangiopathic haemolytic anemia, thrombocytopenia and organ damage. In severe cases STEC-HUS can cause severe neurological complications and can be fatal. We present a patient with a medical history of refractory ulcerative colitis, where making the diagnosis of STEC-HUS was challenging since the initial clinical presentation was difficult to differentiate from a flare of ulcerative colitis. This case illustrates that STEC induced colitis can mimic acute severe ulcerative colitis. This finding is of utmost clinical importance because of the potential life-threatening complications of STEC-HUS. Therefore it should be excluded promptly in patients with acute severe ulcerative colitis by using multiplex-PCR assay on a faecal sample.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Colite Ulcerativa
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Colite
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Infecções por Escherichia coli
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Escherichia coli Shiga Toxigênica
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Síndrome Hemolítico-Urêmica
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article