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Gynecological sarcomas, surgical management: primary, metastatic, and recurrent disease.
Ferron, Gwenael; Bataillon, Guillaume; Martinez, Alejandra; Chibon, Frederic; Valentin, Thibaud.
Afiliação
  • Ferron G; Surgical Oncology, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France ferron.gwenael@iuct-oncopole.fr.
  • Bataillon G; OncoSARC (Oncogenesis of Sarcoma), INSERM UMR1037, Toulouse, France.
  • Martinez A; Anatomopathology, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France.
  • Chibon F; Surgical Oncology, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France.
  • Valentin T; T2i (Anti-tumour immunity and immunotherapy), INSERM UMR1037, Toulouse, France.
Int J Gynecol Cancer ; 34(3): 393-402, 2024 Mar 04.
Article em En | MEDLINE | ID: mdl-38438176
ABSTRACT
Adult-type gynecological soft tissue and visceral sarcomas are rare tumors, with an estimated incidence of 13% of all sarcomas and 4% of all gynecological malignancies. They most often develop in the uterus (83%), followed by the ovaries (8%), vulva and vagina (5%), and other gynecological organs (2%). The objective of this review is to provide an overview of the current management of gynecological sarcomas, according to international guidelines. The management of gynecological sarcomas should follow the recommendations for the management of soft tissue and visceral sarcomas. Centralizing cases in expert centers improves patient survival, both for the diagnostic phase and for multidisciplinary therapeutic management. In the case of pelvic soft tissue sarcomas, a radiological biopsy is essential before any surgical decision is taken. In the case of a myometrial tumour which may correspond to a sarcoma, if conservative surgery such as myomectomy or morcellation is planned, an ultrasound-guided biopsy with pathological analysis including comparative genomic hybridization analysis must be carried out. In all cases, en bloc surgery, without rupture, is mandatory. Many rare histological subtypes require specific surgical management.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma / Morcelação / Ginecologia Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma / Morcelação / Ginecologia Idioma: En Ano de publicação: 2024 Tipo de documento: Article