Nicolau syndrome following glatiramer acetate for multiple sclerosis: Case and review of reports.
Ann Clin Transl Neurol
; 11(4): 1080-1085, 2024 Apr.
Article
em En
| MEDLINE
| ID: mdl-38483009
ABSTRACT
Nicolau syndrome is a rare, iatrogenic skin reaction after parental drug administration, characterized by severe pain at an injection site, followed by hemorrhage, ulceration, and often necrosis. We present a case of a patient on glatiramer acetate for many years (initially Copaxone then Glatopa) who developed Nicolau syndrome, the second reported case after generic glatiramer acetate. All reported cases of Nicolau syndrome after glatiramer acetate are reviewed. The case highlights the importance of prompt recognition of this skin reaction by neurologists and raises awareness of the risks of skin reactions even in low-risk injectable DMTs.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Síndrome de Nicolau
/
Esclerose Múltipla
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article