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Hepatic encephalopathy precipitated by preeclampsia in the setting of cirrhosis: A case report.
Fang, Mary E; Peoples, Nicholas A; Goulding, Alison N; Tolcher, Mary C.
Afiliação
  • Fang ME; Baylor College of Medicine, Houston, TX 77030, United States of America.
  • Peoples NA; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, United States of America.
  • Goulding AN; Baylor College of Medicine, Houston, TX 77030, United States of America.
  • Tolcher MC; Baylor College of Medicine, Houston, TX 77030, United States of America.
Case Rep Womens Health ; 41: e00587, 2024 Mar.
Article em En | MEDLINE | ID: mdl-38515998
ABSTRACT
Preeclampsia and decompensated chronic liver disease are known triggers of acute hepatic dysfunction in pregnancy, rarely including hepatic encephalopathy. Differentiating the driver of acute hepatic dysfunction in patients with concomitant preeclampsia and preexisting liver disease presents a diagnostic challenge with important management implications. A 42-year-old woman, gravida 3 para 0201, at 24 1/7 weeks of gestation presented with hepatic encephalopathy, transaminitis, and hyperbilirubinemia in the setting of cirrhosis and severe new-onset preeclampsia. The preeclampsia was thought to be the leading etiology of hepatic encephalopathy, prompting emergent Cesarean delivery at 24 2/7 weeks. Hepatic encephalopathy, blood pressure, and laboratory derangements improved promptly post-delivery. Preeclampsia can trigger acute hepatic dysfunction, including hepatic encephalopathy, in the setting of previously compensated preexisting liver disease. Recognizing this association has important implications for management and treatment.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article