Development of Midbrain Dopaminergic Neurons and the Advantage of Using hiPSCs as a Model System to Study Parkinson's Disease.

Samson, Jennifer Sally; Ramesh, Anuradha; Parvathi, Venkatachalam Deepa

Samson, Jennifer Sally; Ramesh, Anuradha; Parvathi, Venkatachalam Deepa.

Afiliação

Samson JS; Department of Biomedical Sciences, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai 600116, India.
Ramesh A; Department of Biomedical Sciences, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai 600116, India.
Parvathi VD; Department of Biomedical Sciences, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai 600116, India. Electronic address: deepaparvathi@sriramachandra.edu.in.

Neuroscience ; 546: 1-19, 2024 May 14.

Article em En | MEDLINE | ID: mdl-38522661

Assuntos

Neurônios Dopaminérgicos; Células-Tronco Pluripotentes Induzidas; Mesencéfalo; Doença de Parkinson; Neurônios Dopaminérgicos/metabolismo; Neurônios Dopaminérgicos/patologia; Humanos; Doença de Parkinson/metabolismo; Doença de Parkinson/patologia; Mesencéfalo/metabolismo; Mesencéfalo/patologia; Células-Tronco Pluripotentes Induzidas/metabolismo; Animais; Diferenciação Celular/fisiologia

Palavras-chave

Parkinson's disease; dopamine; drug screening; gene expression; hiPSCs; mDA neurons

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Mesencéfalo / Células-Tronco Pluripotentes Induzidas / Neurônios Dopaminérgicos Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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