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Thyroidectomy Effects on the Body Mass Index and Thyroid-Stimulating Hormone: A Systematic Review and Meta-Analysis.
Mirghani, Hyder; Fnjan, Ahmad M; Almalki, Abdullah F; Almadan, Ali F; Alammar, Omar Abdullah M; Alhwiati, Abdulaziz S; Laradhi, Amer A; Bakour, Ahmed M; Aljahed, Mohamad A; Alzahrani, Abdulmajeed M.
Afiliação
  • Mirghani H; Department of Internal Medicine, University of Tabuk, Tabuk, SAU.
  • Fnjan AM; Department of Internal Medicine, King Abdulaziz University Hospital, Jeddah, SAU.
  • Almalki AF; Department of Internal Medicine, University of Tabuk, Tabuk, SAU.
  • Almadan AF; Department of Internal Medicine, University of Tabuk, Tabuk, SAU.
  • Alammar OAM; Department of Internal Medicine, King Fahad Hospital, Al Hofuf, SAU.
  • Alhwiati AS; Department of Internal Medicine, University of Tabuk, Tabuk, SAU.
  • Laradhi AA; Department of Internal Medicine, King Abdulaziz University Hospital, Jeddah, SAU.
  • Bakour AM; Department of Internal Medicine, University of Tabuk, Tabuk, SAU.
  • Aljahed MA; Department of Internal Medicine, University of Tabuk, Tabuk, SAU.
  • Alzahrani AM; Department of Internal Medicine, University of Tabuk, Tabuk, SAU.
Cureus ; 16(2): e54585, 2024 Feb.
Article em En | MEDLINE | ID: mdl-38524065
ABSTRACT
Thyroidectomy is common and is performed for malignancy, goiters with pressure symptoms, and certain types of Grave's disease. Weight and body mass index (BMI) following thyroidectomy were discussed controversially. This meta-analysis aimed to assess weight and BMI following thyroidectomy. A systematic literature search was conducted in PubMed, Medline, and Google Scholar with interest in articles that assessed body weight and BMI following total or subtotal thyroidectomy. The search engine was limited to the period from inception up to January 2024. Keywords "total thyroidectomy", "subtotal thyroidectomy", "Graves' disease", "multinodular goiter", "differentiated thyroid carcinoma", and "toxic nodules" were used. Out of the 634 articles retrieved, 89 full texts were screened, and only six studies (five retrospective and one prospective cohort) fulfilled the inclusion and exclusion criteria. No differences were evident regarding weight and BMI before and after thyroidectomy (odds ratio -0.63, 95%CI -1.50 to -0.24, P-value for the overall effect 0.15; and odds ratio -0.12, 95% CI -0.41 to -0.16, P-value for the overall effect 0.40 respectively). No heterogeneity was observed (I2 for heterogeneity 0.0%). No association between thyroidectomy (when performed for differentiated thyroid carcinoma and hyperthyroidism), weight, and BMI was found. Further studies assessing thyroid-stimulating hormone (TSH) levels, radioactive iodine therapy, and thyroxine dose are needed.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article